research focus

The VIA program is designed to support clinical research in cystic fibrosis (CF) and applications for clinical research projects will be considered across the entire field of CF.

Clinical research relates to patient-oriented research, including interventional, epidemiological and translational studies.

Please note that any research studies related to Vertex products (either currently on the market or under clinical development) or those focused on non-clinical research, are not eligible for entry.

application process

The application process will be as follows:


Applicant downloads LOI form from VIA website


Applicant submits completed LOI via email


VIA Committee reviews submitted LOIs against selection criteria


VIA Committee shortlists approximately 10 LOIs compliant with selection criteria to proceed to phase 2 of the application process and the submission of a full proposal


VIA Committee invites shortlisted LOI applicants to submit an FP. Guidelines will be provided to the shortlisted applicants


Applicant submits FP as a Word document via email


VIA Committee reviews FPs against selection criteria


VIA Committee selects 1 - 4 FPs for a grant award, with a combined total value up to


VIA Committee provides feedback to all FP applicants



VIA Committee announces details of selected project(s) awarded a grant



Applications are welcome from medical or research centers with a demonstrated record of research and achievement in CF.

Applications are welcome from single centers or multi-centers participating in collaborative research. For all applications, however, a lead investigator center needs to be nominated.

Applications will be eligible from centers in all countries provided the lead investigator center is from one of the following countries:

  • Australia
  • Austria
  • Belgium
  • Brazil
  • Canada
  • Czech Republic
  • Denmark
  • France
  • Germany
  • Greece
  • Italy
  • Israel
  • Ireland
  • The Netherlands
  • New Zealand
  • Norway
  • Poland
  • Portugal
  • Spain
  • Sweden
  • Switzerland
  • UK
  • USA

Applications from centers in countries that are not listed above are most welcome provided that they partner with a center from one of the above listed countries which will act as the lead center.

Applicants should be able to demonstrate that the proposed research will be led by an individual (or individuals) with an established career interest in CF and that they hold an MD, PhD or equivalent degree at the time of the application.

Applicants should be able to complete the proposed research within a 2-year award period, providing interim evidence to the VIA Committee approximately every 6 months, according to their project milestones. The VIA Committee will confirm the reporting requirements at the selection of the final project. Applications should also show the ability to follow local and international requirements (ICH).

All applications need to be supported by the institution hosting the research. An authorized signatory will be required for the submission of the Letter of Intent application.

Grants awarded under this program should not duplicate funding from other government, non-governmental or industry sources. In addition, applications will not be accepted from members or centers of members of the VIA Committee.

selection criteria

The communication, review and selection of applicants and their applications is undertaken by the VIA Committee. Vertex remains independent of the entire application and selection process and has no communication with applicants until the final candidates are selected by the VIA Committee.

Applications will be reviewed and scored by the VIA Committee using a score card according to the following selection criteria:

A. Quality of proposal idea (30% weighting)

Innovation of research; feasibility of research; alignment to the VIA program's research focus

B. Ability of the PI/Group to deliver the project (30% weighting)

Experience and record of executing research projects of comparable scope, expertise, time, budget; experience and record of research center in therapy area; quality and availability of resources; adherence to ethical principles; design, execution and monitoring of the research by the principal investigator; reasonable approach to budget

C. Impact of project on understanding or treatment of CF (40% weighting)

dates & deadlines

February 2020

LOI Application Period Opens

June 30, 2020

LOI Application Period Closes

August 15, 2020

Communication to Shortlisted LOI Applications and Circulation of FP Application Form

August 31, 2020

FP Application Period Closes

October 15, 2020

Communication to Successful Applicant(s)


Timelines may change at the discretion of the Vertex VIA Team and all applicants/potential applicants will be notified accordingly.

contact us

contact us

Should you have any queries regarding the VIA program or the process of submitting a proposal, please email the Vertex VIA Team at the email below.


Please note that the information you submit will be processed by Vertex and its global affiliates for appropriate use relating to VIA or as necessary to comply with Vertex's legal obligations, as further described in the Vertex Privacy Notice, which can be found at